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also known as: GH Stack Blend, CJC/Ipa Blend
Half-life: CJC No DAC: ~30 min; Ipamorelin: ~2 hours
The most popular growth hormone optimization stack, combining CJC-1295 (No DAC) — a GHRH analog that stimulates pituitary GH release — with Ipamorelin, a selective ghrelin mimetic. Together they produce a strong, clean GH pulse with minimal side effects compared to exogenous HGH.
Mechanism of Action
CJC-1295 binds and activates GHRH receptors on somatotrophs; Ipamorelin binds ghrelin/GH secretagogue receptors. Dual-receptor activation produces synergistic GH release up to 10x baseline while preserving pulsatility.
IGF-LR3 adds downstream anabolic signaling that GH peptides do not directly provide.
MK-677 provides 24-hour GH elevation vs the pulsatile action of CJC/Ipa — additive but monitor for water retention.
Tesamorelin specifically targets visceral fat; stacking adds targeted fat loss on top of general GH optimization.
Already contained in this blend.
Already contained in this blend.
GHRP-2 serves the same ghrelin-receptor role as Ipamorelin — redundant when Ipamorelin is already present.
GHRP-6 is redundant with Ipamorelin for GH secretion.
After the No DAC cycle, transition to CJC-1295 with DAC for longer-acting GH elevation with once-weekly dosing.
Storage
Refrigerate at 2–8°C (36–46°F) after reconstitution. 30-day stability.
Reconstitution
Reconstitute each separately with bacteriostatic water, then combine or inject separately.